For the first time in U.S. history, American doctors have delivered a baby girl from a deceased donor's transplanted womb.
The baby was delivered by cesarean section in June at the Cleveland Clinic in Ohio, as per what officials of the hospital said on Tuesday. The birth is part of a clinical trial for uterine transplants working towards treating uterine factor infertility (UFI).
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The trial has involved 10 women, with the mother of the baby girl being the third successful candidate to receive a transplant, fall pregnant and give birth to a healthy baby.
The women in the trial have UFI, which according to the Clinic means "Women who have UFI don't have a uterus or had their uterus removed, so they aren't able to get pregnant."
An estimated one in 5,000 women of child-bearing age is affected by the condition.
It's a wonderful gift of life to see babies now being born through uterine transplants.
Dr. Uma Perni, a maternal fetal medicine specialist at the Cleveland Clinic said: "We couldn't have asked for a better outcome."
It was no easy feat. The research team included a range of transplant specialists, obstetrics and gynecology, fertility, neonatology, bioethics, psychiatry, nursing, anesthesiology, infectious disease, interventional radiology, patient advocacy, and social work.
"It was amazing how perfectly normal the delivery was, considering how extraordinary the occasion," said Dr. Andreas Tzakis, a transplant surgeon at the Cleveland Clinic.
Tzakis continued, "Through this research, we aim to make these extraordinary events ordinary for the women who choose this option. We are grateful to the donor. Their generosity allowed our patient's dream to come true and a new baby to be born."
This is the first U.S. birth from a deceased donor. However, the first recorded birth of this kind was in Brazil in 2017.
The clinical trial involves 10 women aged between 21 and 39 years of age.
Two of the women on the trial are waiting on embryo transfers, and several are waiting for a transplant. Two other transplant attempts were unsuccessful.